Does PGT-A improve IVF success?
It depends entirely on how you measure success, and this is where most of the confusion comes from. Per embryo transfer: yes, rates look higher. You are transferring pre-selected embryos. Per cycle started, or per egg retrieval: the picture changes considerably. Cycles where no embryo passed testing count in this denominator, and PGT-A has not been shown to improve live birth rates measured this way for most patients. ASRM (2026) states that PGT-A has not been shown to significantly reduce miscarriage or improve live births compared with expectant management, and that patients should be counselled it has not been shown to reduce time to successful pregnancy or increase live birth rate. So when a clinic quotes a success rate for PGT-A, the essential question is: is that per transfer or per cycle started? Where PGT-A may reasonably be discussed: ASRM notes that in women over 40 with a proven aneuploid miscarriage, it is reasonable to discuss PGT-A using shared decision-making to reduce miscarriage due to aneuploidy โ with the counselling caveats above. What PGT-A definitely does not do is improve your embryos. The number of chromosomally normal embryos you have is determined before testing. PGT-A identifies them; it does not increase them. If you have few embryos, testing may leave you with nothing to transfer in that cycle โ a real risk to weigh rather than a theoretical one.
Review by Fertility Connect Medical Team Pending
This information is general and does not replace advice from your own clinician.