Is prenatal testing still needed after PGT-M?

ESHRE's recommendation is clear: prenatal diagnosis should be offered to all women who become pregnant following PGT. That is not a suggestion that PGT is unreliable. It reflects that a residual risk of misdiagnosis always remains, however small, and that you should be given the opportunity to confirm the result. ESHRE also specifies that the discussion of available tests should be undertaken by a suitably qualified professional so that all options are presented — including invasive diagnostic tests such as CVS and amniocentesis, and non-invasive options such as ultrasound and cell-free fetal DNA testing. If you would prefer to avoid an invasive procedure, there is an alternative: postnatal confirmation using cord blood at delivery. ESHRE notes this as an option, with the caveat that testing children for conditions that cannot be acted on should follow local law. Ask for this to be arranged in advance rather than remembered on the day. ESHRE also recommends that when a pregnancy occurs after PGT, parents are made aware again of the chance and risks of misdiagnosis and informed about prenatal testing options — so this conversation should happen a second time, not just before your cycle. Whether you take up prenatal diagnosis is your choice. Some couples want confirmation; others, having already been through PGT, prefer not to face another decision. Both are legitimate. What matters is that you are offered it.