Who should do PGT-A?

There is no universally agreed list, because the benefit is contested. What follows is where discussion is reasonable rather than where it is recommended. Situations where PGT-A is commonly discussed: Advanced maternal age, where a higher proportion of embryos are chromosomally abnormal. ASRM specifically notes it is reasonable to discuss in women over 40 with a proven aneuploid miscarriage. Recurrent pregnancy loss — though note that women with recurrent loss have a higher likelihood of euploid miscarriage, which limits what PGT-A can address. Repeated implantation failure with good-quality embryos. Where many embryos are available and a transfer order must be chosen. Situations where it is less likely to help: Few embryos available. Testing may leave you with none to transfer. Younger women with good embryo numbers, where most embryos are euploid anyway. As a routine addition without a specific reason. Questions worth asking your clinic: What is your live birth rate per cycle started, with and without PGT-A, for someone in my situation? How many embryos would you expect me to have, and what happens if none pass? What is your policy on mosaic embryos? What does it cost, and what is the additional cost of freezing and a later transfer? If the answer to why it is being recommended is that it is standard practice here, that is not a clinical indication. Ask what it would achieve for you specifically.